First Case of TAP1 Deficiency with EBV B-Cell Lymphoma Treated with Cellular Immunotherapy

Francisco Javier Bermejo-Olivera; Miriam Velasco-Sidro; Rodrigo Íñiguez-García; Daniel Arroyo-Sánchez; Daniel Enrique Pleguezuelo-Garrote; Manuel Serrano-Blanco; Aurora Fernández-Galván; Tycho Baumann; Francisco Javier López-Jiménez; Enrique Revilla-Sánchez; Estela Paz-Artal; Luis M Allende; Oscar Cabrera-Marante

doi:10.1007/s10875-026-01997-0

First Case of TAP1 Deficiency with EBV B-Cell Lymphoma Treated with Cellular Immunotherapy

J Clin Immunol. 2026 Apr 9. doi: 10.1007/s10875-026-01997-0. Online ahead of print.

Authors

Francisco Javier Bermejo-Olivera^#^{1

2}, Miriam Velasco-Sidro^#^{1

2}, Rodrigo Íñiguez-García³, Daniel Arroyo-Sánchez^{1

2}, Daniel Enrique Pleguezuelo-Garrote^{1

2}, Manuel Serrano-Blanco^{1

2}, Aurora Fernández-Galván⁴, Tycho Baumann³, Francisco Javier López-Jiménez⁵, Enrique Revilla-Sánchez⁶, Estela Paz-Artal^{1

2}, Luis M Allende^{1

2}, Oscar Cabrera-Marante^{7

8

9}

Affiliations

¹ Immunology Department, University Hospital 12 de Octubre, Madrid, Spain.
² Research Institute Hospital Universitario 12 de Octubre (Imas12), Madrid, Spain.
³ Hematology Department, University Hospital 12 de Octubre, Madrid, Spain.
⁴ Dermatology Department, Hospital La Princesa, Madrid, Spain.
⁵ Hematology Department, University Hospital Ramón y Cajal, Madrid, Spain.
⁶ Pathology Anatomy Department, University Hospital 12 de Octubre, Madrid, Spain.
⁷ Immunology Department, University Hospital 12 de Octubre, Madrid, Spain. ocabreramarante@gmail.com.
⁸ Research Institute Hospital Universitario 12 de Octubre (Imas12), Madrid, Spain. ocabreramarante@gmail.com.
⁹ HM Health Sciences faculty, Universidad Camilo José Cela, Madrid, Spain. ocabreramarante@gmail.com.

^# Contributed equally.

PMID: 41954665
DOI: 10.1007/s10875-026-01997-0

No abstract available

Keywords: Adoptive immunotherapy; B-Cell lymphoma; Bare lymphocyte syndrome, type I.; Epstein-Barr virus infections; Inborn errors of immunity (IEI); Lymphoproliferative disorders.

Grants and funding

P177122021/Mutual Madrileña