Extended Characterisation of the Coding Sequence of the HLA-A*02:97:01 Allele by Next and Third-Generation Sequencing

HLA. 2026 Apr;107(4):e70708. doi: 10.1111/tan.70708.

Abstract

HLA-A*02:97:01 differs from HLA-A*02:01:01:01 by a single nucleotide substitution in codon 232 within exon 4.

Keywords: HLA‐A*02:97:01; HLA; Oxford Nanopore Technologies; rare allele; sequencing‐by‐synthesis.

Publication types

  • Letter

MeSH terms

  • Alleles*
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • HLA-A2 Antigen* / genetics
  • HLA-A2 Antigen* / immunology
  • High-Throughput Nucleotide Sequencing*
  • Histocompatibility Testing
  • Humans
  • Polymorphism, Single Nucleotide*
  • Sequence Analysis, DNA

Substances

  • HLA-A2 Antigen
  • Codon
  • HLA-A*02 antigen