Methodological considerations regarding factors contributing to missed injuries in trauma patients

Injury. 2026 Apr 3:113240. doi: 10.1016/j.injury.2026.113240. Online ahead of print.

Abstract

This correspondence addresses the recent study by Yeo et al., which identified polytrauma and night-time presentation as independent risk factors for missed injuries (MIs) in trauma patients. While acknowledging the study's contribution to trauma system evaluation, we highlight three critical methodological limitations that affect the interpretation of these findings. First, the significantly longer hospital stay in the MI group (41.3 days vs. 21.5 days) suggests a substantial detection bias, where prolonged hospitalization increases the likelihood of incidentally diagnosing Type II injuries. Second, a "history bias" exists due to the absence of orthopaedic trauma surgeons during the majority of the study period (2019-2023), which likely accounts for the prevalence of musculoskeletal MIs rather than night-time risk alone. Third, the broad definition of "night-time" (8:00 PM - 8:00 AM) conflates shift handover errors with circadian fatigue, obscuring the underlying mechanism of failure. We suggest that future research must control for length of stay and utilize granular time-series analysis to guide precise system-level interventions.

Keywords: Detection bias; Missed injury; Trauma center staffing.

Publication types

  • Letter