The role of the cGAS/STING pathway in skeletal muscle regeneration: modulation of inflammation, macrophage polarization, and oxidative stress

Cell Mol Biol Lett. 2026 Apr 13. doi: 10.1186/s11658-026-00908-w. Online ahead of print.

Xiaoguang Liu^#^{1

2}, Hao Wang^#¹, Miaomiao Xu^#³, Huan Wang¹, Haozhe Wang¹, Wenjun Fang¹, Mengqian Li¹, Jiongxing Huang¹, Huiguo Wang^{1

2}, Yang Yu^{1

2}, Lin Zhu^{4

5}

¹ School of Sport and Health, Guangzhou Sport University, Guangzhou, 510500, China.
² Research Center for Innovative Development of Sports and Healthcare Integration, Guangzhou Sport University, Guangzhou, 510500, China.
³ Department of Physical Education, Guangdong University of Education, Guangzhou, 510303, China.
⁴ School of Sport and Health, Guangzhou Sport University, Guangzhou, 510500, China. 11251@gzsport.edu.cn.
⁵ Innovative Research Center for Sports Science in the Guangdong-Hong Kong-Macao Greater Bay Area, Guangzhou Sport University, Guangzhou, 510500, China. 11251@gzsport.edu.cn.

^# Contributed equally.

No abstract available

Keywords: Macrophages; Regeneration; STING; Skeletal muscle; cGAS.

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