Association of Coverage-Promoting Policies With Initiation and Discontinuation of Buprenorphine Treatment During Medicaid Unwinding

J Addict Med. 2026 Apr 14:10.1097/ADM.0000000000001695. doi: 10.1097/ADM.0000000000001695. Online ahead of print.

Abstract

Objectives: We examined associations between coverage-promoting policies and changes in initiation and discontinuation of buprenorphine treatment during Medicaid unwinding.

Methods: We conducted a retrospective analysis of national retail pharmacy data (2021-2023) to examine the association between 4 separate coverage-promoting policies and the number of initiations and discontinuations of buprenorphine treatment episodes in the 6 months after unwinding began. Statistical significance was assessed using 2-sample t tests.

Results: Following up with enrollees nonresponsive to renewal requests and improving ex parte renewal rates were associated with smaller decreases in initiations (-1.4 percentage point difference [pp] [95% CI: -1.5 to -1.4] and -1.5 pp [95% CI: -1.5 to -1.5], respectively) and smaller increases in discontinuations (0.6 pp [95% CI: 0.5-0.7] and 0.6 pp [95% CI: 0.6-0.7], respectively). Following up on returned mail and mostly automated renewal processing had mixed effects. Following up on returned mail was associated with a larger decrease in initiations (1.1 pp [95% CI: 1.0-1.2]) but a smaller increase in discontinuations (1.1 pp [95% CI: 1.0-1.2]); automated renewal processing was associated with a smaller decrease in initiations (-1.6 pp [95% CI: -1.6 to -1.6]) but a larger increase in discontinuations (-2.5 pp [95% CI: -2.6 to -2.5]).

Conclusions: Some coverage-promoting policies were associated with smaller disruptions in buprenorphine treatment during Medicaid unwinding; potential protective effects varied by policy type.

Keywords: Medicaid; buprenorphine; opioid use disorder; state policies.