Total Aortic Arch Replacement With the Frozen Elephant Trunk Technique: Influence of Aortic Arch Anomalies

Interdiscip Cardiovasc Thorac Surg. 2026 May 5;41(5):ivag100. doi: 10.1093/icvts/ivag100.

Abstract

Objectives: To assess surgical challenges and outcomes associated with arch anomalies in patients undergoing frozen elephant trunk (FET) for acute and chronic dissections.

Methods: From January 2007 to January 2024, 401 patients underwent FET procedure in our centre. We included 285 patients with acute type A/B, chronic type A/B, and residual dissection. Patients were divided into normal arch group (n = 216) and arch anomalies group (n = 69), including aberrant right subclavian artery, bovine trunk, arch vertebral artery, and gothic arch.

Results: Overall in-hospital mortality was 15.4% (17.4% in arch anomalies vs 14.8% in arch normal). In-hospital thoracic endovascular aortic repair (TEVAR) occurred in 7.2% (n = 5) of patients with arch anomalies. Stent graft-induced new entry tear at follow-up was 26.1% in arch anomalies vs 17.1% in arch normal group. Long-term survival in the overall patients was not different between the 2 groups (P = .383). In the subgroup of patients treated for chronic aortic dissection, freedom from TEVAR was higher in those with normal arch anatomy (P = .026).

Conclusions: Aortic arch anomalies, especially in chronic dissection, were associated with increased endovascular reintervention. The gothic arch is the most challenging configuration due to frequent stent kinking.

Keywords: aortic arch anomalies; aortic dissection; frozen elephant trunk; thoracic endovascular aortic repair.

MeSH terms

  • Adult
  • Aged
  • Aorta, Thoracic* / abnormalities
  • Aorta, Thoracic* / diagnostic imaging
  • Aorta, Thoracic* / surgery
  • Aortic Aneurysm, Thoracic* / diagnostic imaging
  • Aortic Aneurysm, Thoracic* / mortality
  • Aortic Aneurysm, Thoracic* / surgery
  • Aortic Dissection* / diagnostic imaging
  • Aortic Dissection* / mortality
  • Aortic Dissection* / surgery
  • Blood Vessel Prosthesis
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Blood Vessel Prosthesis Implantation* / instrumentation
  • Blood Vessel Prosthesis Implantation* / methods
  • Blood Vessel Prosthesis Implantation* / mortality
  • Endovascular Procedures* / adverse effects
  • Endovascular Procedures* / instrumentation
  • Endovascular Procedures* / mortality
  • Female
  • Hospital Mortality
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / mortality
  • Retrospective Studies
  • Stents
  • Treatment Outcome