Associations between cholesterol, high-density lipoprotein, and glucose index and hyperuricemia in patients with diabetes

Zhihan Wang; Xuemin Peng; Zengzhe Zhu; Ziyin Zhang; Yaming Guo; Peng Yu; Limeng Pan; Xuefeng Yu; Min Yang; Yong Chen

doi:10.1186/s12902-026-02281-3

Associations between cholesterol, high-density lipoprotein, and glucose index and hyperuricemia in patients with diabetes

BMC Endocr Disord. 2026 Apr 17. doi: 10.1186/s12902-026-02281-3. Online ahead of print.

Authors

Zhihan Wang^{1

2}, Xuemin Peng^{1

2}, Zengzhe Zhu^{1

2}, Ziyin Zhang^{1

2}, Yaming Guo^{1

2}, Peng Yu^{1

2}, Limeng Pan^{1

2}, Xuefeng Yu^{1

2

3

4}, Min Yang⁵, Yong Chen^{6

7

8

9

10}

Affiliations

¹ Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.
² Laboratory of Endocrinology and Metabolism, Key Laboratory of Vascular Aging, Ministry of Education, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
³ Hubei Clinical Medical Research Center for Endocrinology and Metabolic Diseases, Wuhan, China.
⁴ Branch of National Clinical Research Center for Metabolic Diseases, Wuhan, China.
⁵ Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China. yangmin87420@163.com.
⁶ Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China. tj.y.chen@vip.163.com.
⁷ Laboratory of Endocrinology and Metabolism, Key Laboratory of Vascular Aging, Ministry of Education, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. tj.y.chen@vip.163.com.
⁸ Hubei Clinical Medical Research Center for Endocrinology and Metabolic Diseases, Wuhan, China. tj.y.chen@vip.163.com.
⁹ Branch of National Clinical Research Center for Metabolic Diseases, Wuhan, China. tj.y.chen@vip.163.com.
¹⁰ Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, Hubei Province, 430030, PR China. tj.y.chen@vip.163.com.

PMID: 41998543
DOI: 10.1186/s12902-026-02281-3

No abstract available

Keywords: Cholesterol, high-density lipoprotein, and glucose index; Hyperuricemia; Type 2 diabetes mellitus.

Grants and funding

82270910/National Natural Science Foundation of China