Obesity and cancer: Methodological frontiers for mechanistic discoveries

PLoS Med. 2026 Apr 24;23(4):e1005081. doi: 10.1371/journal.pmed.1005081. eCollection 2026 Apr.

Abstract

It has long been a biological mystery why obesity increases cancer risk. Rapid advances in statistical and analytical methods are now opening the door to mechanistic discoveries that may finally resolve this question.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Neoplasms* / epidemiology
  • Neoplasms* / etiology
  • Obesity* / complications
  • Obesity* / epidemiology
  • Risk Factors