In inpatients with acute-on-chronic liver failure, suspicion- vs. investigation-based antifungal therapy increased survival at 28 d

Ann Intern Med. 2026 May;179(5):JC58. doi: 10.7326/ANNALS-26-01051-JC. Epub 2026 May 5.

Authors

Marwan Ghabril¹, Nicolas Barros¹; ACP Journal Club Editorial Team at McMaster University

Affiliation

¹ Indiana University School of Medicine, Indianapolis, Indiana, USA (M.G., N.B.).

PMID: 42081819
DOI: 10.7326/ANNALS-26-01051-JC

Abstract

GIM/FP/GP:[Formula: see text] Gastroenterology:[Formula: see text] Critical Care:[Formula: see text].

MeSH terms

Acute-On-Chronic Liver Failure* / complications
Acute-On-Chronic Liver Failure* / drug therapy
Acute-On-Chronic Liver Failure* / mortality
Antifungal Agents* / therapeutic use
Humans
Mycoses* / complications
Mycoses* / diagnosis
Mycoses* / drug therapy

Substances

Antifungal Agents