Background: The integrity of the skin barrier is fundamental to maintaining overall skin health, serving as the primary defense against environmental insults. Disruption of this barrier is linked to various dermatological issues, including inflammation, sensitivity, and premature aging. Therefore, technologies designed to reinforce the skin barrier and enhance moisture retention hold a significant promise for improving skin condition, resilience, and overall function.
Aims: To evaluate the restorative effect of DYNAMiQ technology on skin barrier function.
Methods: This prospective, single-center study enrolled 24 female subjects (n = 24, 26-64 years). Each subject received one DYNAMiQ treatment, with a follow-up assessment performed 7 days later. Transepidermal water loss (TEWL) was measured before treatment, immediately after, and at follow-up. Subject-reported outcomes were collected using comfort and satisfaction questionnaires, and standardized photographs were taken.
Results: TEWL increased slightly from a baseline of 11.95 ± 0.24 g/m2/h to 12.70 ± 0.19 g/m2/h immediately post-treatment. By day 7, TEWL decreased significantly to 6.63 ± 0.18 g/m2/h, representing an 80.3% improvement in water vapor loss. All subjects (100%) expressed satisfaction with the results, and 96% reported that their skin felt more hydrated and nourished.
Conclusions: DYNAMiQ technology effectively improves skin barrier function by significantly reducing TEWL. These findings are supported by high subject satisfaction and perceived hydration improvements.
Keywords: TEWL; calcium gradient; hydration; skin barrier; skin health.
© 2026 The Author(s). Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.