Opioid-related mortality is a global issue, and France shows high opioid use disorder indicators. Despite recommendations for wider take-home-naloxone distribution, access remains limited in France, and many primary care professionals lack training. The SINFONI project aims to enhance naloxone education for these providers. A motion-design training program was created and sent to general practitioners (GPs) and pharmacists. A total of 138 GPs and 207 pharmacists participated in the knowledge assessment before and after training. Post-training, significant improvements were observed, and the greatest knowledge gains were in understanding naloxone's safety (P < .001). Our findings primarily identified critical "red flags" that may hinder prescription and dispensing practices.
© The Author(s) 2026. Published by Oxford University Press on behalf of the European Public Health Association.