Observed frequency of increased iron indices and associated factors in welders

Arch Environ Occup Health. 2026;81(7-8):171-182. doi: 10.1080/19338244.2026.2671046. Epub 2026 May 11.

Abstract

Increased iron indices among welders are underrecognized. This study investigated their frequency and associated factors in an observational cross-sectional study including 55 male welders. Increased iron indices were defined as serum ferritin >400 µg/L and/or TS ≥45%. Standard statistical and regression analyses were used. Increased iron indices were identified in 25.5% of welders. Compared to those with normal indices, affected welders had longer employment duration. Iron parameters were significantly higher in the increased group (serum iron 139.6 vs. 93.3 µg/dL, ferritin 498.9 vs. 142.3 µg/L, TS 47.7% vs. 28.9%; all p<0.001). Liver enzymes were also higher in this group. Pulmonary siderosis was more prevalent (64.3% vs. 31.7%; p=0.032) and associated with increased iron indices (OR 3.88 [1.08-13.89]; p=0.037). Use of respiratory protective equipment was associated with lower frequency. Increased iron indices are common in welders, particularly with longer exposure and pulmonary siderosis, suggesting a need for routine monitoring.

Keywords: Ferritin; frequency; increased iron indices; transferrin saturation; welders.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Ferritins* / blood
  • Humans
  • Iron* / blood
  • Male
  • Middle Aged
  • Occupational Diseases* / blood
  • Occupational Diseases* / epidemiology
  • Occupational Exposure* / adverse effects
  • Siderosis / epidemiology
  • Welding*

Substances

  • Iron
  • Ferritins