Deterministic and Probabilistic Assessment of Dietary Exposure to Pesticide Residues in Sweet Italian-Type and Jalapeño Peppers From Türkiye for the Adult Population

J Agric Food Chem. 2026 May 27;74(20):15832-15845. doi: 10.1021/acs.jafc.6c00194. Epub 2026 May 12.

Abstract

Pesticide residue contamination in peppers is a food safety concern due to intensive production practices and frequent consumption. In this study, 182 sweet Italian-type and jalapeño pepper samples collected in Türkiye were analyzed for 260 pesticide residues using liquid chromatography-tandem mass spectrometry. Residues were detected in 52.6% of sweet Italian-type and 48.1% of jalapeño samples, with European Union maximum residue level exceedances of 15.8 and 5.7% of all samples, respectively. Deterministic and probabilistic assessments indicated that cumulative chronic dietary exposure remained well below safety thresholds for adults. Monte Carlo simulations consistently identified lambda-cyhalothrin and acetamiprid as the dominant contributors to chronic exposure. Acute risk was generally low; however, high-end exposure scenarios indicated a potential concern associated with lambda-cyhalothrin in jalapeño peppers.

Keywords: Capsicum spp.; LC-MS/MS; Monte Carlo simulation; QuEChERS; cumulative risk assessment; food safety; hazard index.

MeSH terms

  • Capsicum* / chemistry
  • Capsicum* / metabolism
  • Dietary Exposure* / analysis
  • Food Contamination* / analysis
  • Fruit / chemistry
  • Fruit / metabolism
  • Humans
  • Italy
  • Liquid Chromatography-Mass Spectrometry
  • Monte Carlo Method
  • Neonicotinoids / analysis
  • Nitriles / analysis
  • Pesticide Residues* / analysis
  • Pyrethrins / analysis
  • Tandem Mass Spectrometry

Substances

  • Pesticide Residues
  • Pyrethrins
  • cyhalothrin
  • acetamiprid
  • Neonicotinoids
  • Nitriles