Late-Onset Suspected Coronary Vasospasm Following Focal Monopolar Pulsed-Field Ablation for Atrial Fibrillation

J Cardiovasc Electrophysiol. 2026 Jul;37(7):1615-1617. doi: 10.1111/jce.70370. Epub 2026 May 15.

Abstract

Introduction: Coronary vasospasm is a recognized complication of pulsed-field ablation (PFA), but delayed events are rarely described.

Methods and results: A 64-year-old man underwent atrial fibrillation ablation using a focal monopolar PFA catheter. He developed transient chest discomfort 18 h after ablation, followed by sustained chest tightness with ST-segment depression 42 h post-procedure. Symptoms and electrocardiographic changes resolved promptly with sublingual nitroglycerin, suggesting coronary vasospasm.

Conclusion: Coronary vasospasm after focal monopolar PFA may occur beyond the immediate post-procedural period, which may have implications for monitoring and discharge planning.

Publication types

  • Case Reports

MeSH terms

  • Atrial Fibrillation* / diagnosis
  • Atrial Fibrillation* / physiopathology
  • Atrial Fibrillation* / surgery
  • Catheter Ablation* / adverse effects
  • Coronary Vasospasm* / diagnosis
  • Coronary Vasospasm* / drug therapy
  • Coronary Vasospasm* / etiology
  • Coronary Vasospasm* / physiopathology
  • Electrocardiography
  • Humans
  • Irreversible Electroporation Therapy
  • Male
  • Middle Aged
  • Time Factors
  • Treatment Outcome
  • Vasodilator Agents / administration & dosage

Substances

  • Vasodilator Agents