Non-inferiority of digitally assisted outpatient rehabilitation in patients with back pain: 12-month follow-up of a randomized controlled trial

J Rehabil Med. 2026 May 20:58:jrm44366. doi: 10.2340/jrm.v58.44366.

Abstract

Objective: To examine the non-inferiority of digitally assisted, multimodal rehabilitation that utilizes a digital version of a standardized back school (intervention group) compared with a rehabilitation program applying the back school conventionally in person (control group).

Design: Nonblinded, randomized, controlled, non-inferiority trial with 12-month follow-up after the end of rehabilitation.

Subjects/patients: Adults aged 18-65 years with back pain.

Methods: The back school was part of a 3-week rehabilitation program along with other treatments in accordance with the therapy standards. Eight outpatient rehabilitation centers conducted the rehabilitation program. Self-reported pain self-efficacy (10-60 points) was the primary outcome. Non-inferiority was established if the lower limit of the one-sided 95% confidence interval was greater than -4 points for pain self-efficacy.

Results: A total of 157 participants (55.3%) completed the 12-month follow-up. Multiple imputation of missing data allowed for inclusion of 270 participants in the analysis (intervention group: n = 127, control group: n = 143). Our primary adjusted intention- to-treat analysis demonstrated that digitally assisted rehabilitation was non-inferior to conventional rehabilitation at the 12-month follow-up (b = 0.48; 95% CI = -3.09 to ∞).

Conclusion: This study supports the hypothesis that digitally assisted rehabilitation is a viable alternative to in-person rehabilitation for patients with back pain.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Back Pain* / rehabilitation
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Outpatients
  • Pain Measurement
  • Self Efficacy
  • Treatment Outcome
  • Young Adult