The smooth endoplasmic reticulum as a possible storage site for dendritic dopamine in substantia nigra neurones

Experientia. 1979 Jan 15;35(1):101-3. doi: 10.1007/BF01917903.


In dendrites of the substantia nigra neurones the monoamine marker 5-hydroxydopamine injected intracerebrally was localized inside of smooth endoplasmic reticulum cisterns. This observation opens the possibility of the existence of an alternative site for dopamine storage in dendrites as opposed to the well-known vesicular storage.

MeSH terms

  • Animals
  • Dendrites / metabolism*
  • Dendrites / ultrastructure
  • Dopamine / metabolism*
  • Endoplasmic Reticulum / metabolism
  • Male
  • Neurons / ultrastructure
  • Rats
  • Substantia Nigra / metabolism*
  • Substantia Nigra / ultrastructure


  • Dopamine