Abstract
A crude extract of the sciatic nerve, eluate of dialyzed nerve extract or 2 folin-positive sephadex fractions induced acetylcholine sensitivity of extrajunctional regions in extensor digitorum longus muscle fibres of the rat, when released from silastic plates implanted for 3--4 days onto the muscle surface.
MeSH terms
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Acetylcholine / pharmacology*
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Animals
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Cell Differentiation
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Dose-Response Relationship, Drug
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Female
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Membrane Potentials / drug effects
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Motor Endplate / physiology*
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Neuromuscular Junction / physiology*
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Neuromuscular Junction / ultrastructure*
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Peripheral Nerves / physiology*
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Rats
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Receptors, Cholinergic / drug effects
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Sciatic Nerve / physiology
Substances
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Receptors, Cholinergic
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Acetylcholine