Enhancing resolution and image quality in musculoskeletal MRI using deep learning reconstruction

Eur Radiol Exp. 2026 May 28;10(1):78. doi: 10.1186/s41747-026-00743-w.

Abstract

Objective: Deep learning-based noise reduction enhances image quality, overcoming the tradeoff among acquisition time, spatial resolution, and signal-to-noise ratio (SNR). We implemented deep learning reconstruction (DLR) into a 1.5-T musculoskeletal (MSK) magnetic resonance imaging (MRI) protocol to improve image quality without compromising SNR.

Materials and methods: We retrospectively analyzed 39 MRI examinations performed on a 1.5-T scanner using standard-resolution (SR) sequences and sequences with higher resolution reconstructed with DLR (HR-DLR). Exams of the knees, shoulders, ankles, and hips were evaluated. The included sequences were: three-dimensional T2-weighted fast advanced spin-echo; T1-weighted and proton density-weighted fast spin-echo. One expert reader and two junior readers in agreement evaluated the visibility of various structures using a 5-point Likert scale in a blind manner. A fourth reader estimated the SNR and contrast-to-noise ratio (CNR) in bone and muscle. A mixed model was used to compare HR-DLR versus SR measures. The agreement between radiologists was assessed with the Kendall τ coefficient.

Results: The HR-DLR sequences globally had a smaller pixel size and shorter acquisition time. A good inter-reader agreement was obtained for SR sequences (0.613 ≤ τ ≤ 0.788) and even higher levels of agreement for HR-DLR sequences (0.682 ≤ τ ≤ 0.961). All the structures had higher or similar Likert scores in HR-DLR sequences (p < 0.001), regardless of joint and sequence contrast. Apparent SNR and CNR of HR-DLR and SR were similar.

Conclusion: Incorporating DLR into 1.5-T MSK MRI protocols enhances resolution and maintains SNR and CNR, improving MSK structure visualization.

Relevance statement: This study demonstrated the effectiveness of deep learning reconstruction in improving the efficiency of 1.5-T musculoskeletal MRI exams. Despite shorter acquisition times, the visibility of key MSK structures was consistently rated as superior or similar in higher-resolution images with DLR.

Key points: MRI is one of the primary diagnostic tools for evaluating MSK injuries and disorders. Deep learning reconstruction (DLR) implemented in a 1.5-T MSK protocol improved resolution, still preserving SNR and CNR. Higher scores were assigned by different raters to the DLR images, showing image quality improvement.

Keywords: Deep learning; Image processing (computer-assisted); Magnetic resonance imaging; Musculoskeletal system; Signal-to-noise ratio.

MeSH terms

  • Adult
  • Deep Learning*
  • Female
  • Humans
  • Image Processing, Computer-Assisted* / methods
  • Magnetic Resonance Imaging* / methods
  • Male
  • Musculoskeletal System* / diagnostic imaging
  • Retrospective Studies
  • Signal-To-Noise Ratio