Reversible bilateral sensorineural hearing loss associated with atorvastatin: a case report

J Med Case Rep. 2026 Jun 2. doi: 10.1186/s13256-026-06114-8. Online ahead of print.

Abstract

Background: Atorvastatin is widely prescribed for hyperlipidemia and is generally well tolerated. Auditory adverse effects are rarely reported, and statin-associated sensorineural hearing loss (SNHL) remains poorly characterized.

Case presentation: A 45-year-old Ethiopian woman developed bilateral tinnitus followed by progressive, symmetric bilateral SNHL 3 weeks after starting atorvastatin 40 mg daily. She had no other ototoxic risk factors. Pure-tone audiometry confirmed bilateral moderate SNHL. Given the temporal association and exclusion of alternatives, atorvastatin was discontinued. One week later, audiometry showed improvement to mild hearing loss, and at a 1-month follow-up, thresholds normalized with complete symptom resolution. She was subsequently switched to rosuvastatin 20 mg daily, with no recurrence at a 6-month follow-up.

Conclusion: This case demonstrates that atorvastatin-associated SNHL can be reversible when recognized early. Prompt identification of new auditory symptoms and timely discontinuation of the offending medication may prevent permanent hearing impairment.

Keywords: Atorvastatin; Case report; Ototoxicity; Reversible hearing loss; Sensorineural hearing loss; Statin adverse effects.