The Role of Podiatric Treatment in Ledderhose Disease Management

Clin Med Insights Arthritis Musculoskelet Disord. 2026 Jun 1:19:11795441251392297. doi: 10.1177/11795441251392297. eCollection 2026.

Abstract

Ledderhose disease, or plantar fibromatosis, is a rare fibroproliferative disorder affecting the plantar fascia. Conservative management plays a crucial role in alleviating symptoms and maintaining function. This article explores the role of podiatric interventions, including custom orthotics, footwear modifications, manual therapy, and adjunctive modalities such as shockwave therapy. In addition, the role of regenerative medicine and the need for interdisciplinary rehabilitation strategies are discussed. Future research should focus on the efficacy of podiatric treatments and their integration into multidisciplinary care.

Keywords: Ledderhose disease; orthotic therapy; plantar fibromatosis; podiatric rehabilitation.