A rare case of multifocal subglottic-tracheal Rosai-Dorfman disease (RDD) achieved sustained 48-month remission through surgical resection alone, without adjuvant therapy. This outcome suggests that surgery alone may serve as a viable alternative for select cases of multifocal airway RDD characterized by completely resectable lesions, no systemic involvement, and favorable anatomical accessibility.
Keywords: Rosai–Dorfman disease (RDD); adjuvant therapy‐free; case report; multifocal subglottic‐tracheal obstruction; surgical resection.
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