Idiopathic hydronephrosis--the diuresis renogram: a new non-invasive method of assessing equivocal pelvioureteral junction obstruction

J Urol. 1979 Feb;121(2):153-5. doi: 10.1016/s0022-5347(17)56703-8.


A new method to evaluate patients with equivocal obstruction of the pelvioureteral junction is described. It involves the performance of a standard 131iodine-hippuran renogram followed by a second renogram 3 minutes after an intravenous injection of the diuretic, frusemide. When the 2 results are inspected together it is found that the patients can be separated into 4 groups: 1) normal, 2) obstructed, 3) atonic and 4) partially obstructed. The results in 23 children and 27 adults with suspected obstruction of the pelvioureteral junction are presented. Obstruction was confirmed in 18 patients and excluded in 32. The correlation between the renogram results and clinical, radiological and operative findings is discussed. The technique is simple, accurate and non-invasive, and it is recommended after excretory urography before proceeding to more invasive tests.

MeSH terms

  • Adult
  • Child
  • Diuresis* / drug effects
  • Evaluation Studies as Topic
  • Furosemide
  • Humans
  • Hydronephrosis / etiology*
  • Iodohippuric Acid
  • Kidney Pelvis / abnormalities
  • Radioisotope Renography / methods*
  • Ureter / abnormalities
  • Ureteral Obstruction / diagnosis*


  • Iodohippuric Acid
  • Furosemide