A new sense for electrical fields

Michael Riedl; Michael Sixt

doi:10.1016/j.cell.2026.05.038

A new sense for electrical fields

Cell. 2026 Jun 25;189(13):3845-3846. doi: 10.1016/j.cell.2026.05.038.

Authors

Michael Riedl¹, Michael Sixt²

Affiliations

¹ Cluster of Excellence Physics of Life, TU Dresden, Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
² Institute of Science and Technology Austria (ISTA), Am Campus 1, 3400 Klosterneuburg, Austria. Electronic address: sixt@ist.ac.at.

PMID: 42349380
DOI: 10.1016/j.cell.2026.05.038

Abstract

Most cells polarize and migrate in response to electrical fields. In this issue of Cell, Belliveau et al. identify TMEM154/Galvanin, a receptor that serves as a cellular antenna to sense electrical gradients and guide migration toward the cathode.

Publication types

Comment

MeSH terms

Animals
Cell Movement*
Cell Polarity*
Electricity
Humans
Membrane Proteins

Substances

TMEM154 protein, human
Membrane Proteins