Identification of the Novel HLA-B*55:02:18 Allele Using Nanopore Sequencing Technology

HLA. 2026 Jul;108(1):e70871. doi: 10.1111/tan.70871.

Abstract

HLA-B*55:02:18 differs from HLA-B*55:02:01:01 by one nucleotide substitution at position 963 G > A.

Keywords: HLA‐B*55:02:18; nanopore sequencing; novel allele.

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons*
  • HLA-B Antigens* / genetics
  • Histocompatibility Testing
  • Humans
  • Nanopore Sequencing*
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Tissue Donors

Substances

  • HLA-B Antigens