Severe Hypersensitivity Reactions Associated With Allopurinol

JAMA. 1971 May 3;216(5):799-802.

MeSH terms

  • Acute Disease
  • Allopurinol / adverse effects*
  • Arthritis / drug therapy
  • Biopsy
  • Dermatitis, Exfoliative / chemically induced
  • Drug Hypersensitivity / blood
  • Drug Hypersensitivity / drug therapy
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / pathology
  • Eosinophilia / chemically induced
  • Eosinophils
  • Female
  • Gout / drug therapy
  • Humans
  • Liver / pathology
  • Male
  • Middle Aged
  • Prednisone / therapeutic use
  • Pruritus / drug therapy
  • Skin / pathology
  • Time Factors

Substances

  • Allopurinol
  • Prednisone