doi: 10.1007/BF01953252.
Increased release of tumour cells by collagenase at acid pH: a possible mechanism for metastasis
- PMID: 42555
- DOI: 10.1007/BF01953252
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Increased release of tumour cells by collagenase at acid pH: a possible mechanism for metastasis
Experientia.
.
Abstract
The ability of collagenase to disaggregate a solid metastasizing lymphosarcoma has been shown to considerably increase with reducing environmental pH. It is suggested that this effect may be operating in vivo to release cells from a primary tumour.
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