Aminoglutethimide (Elipten-Ciba) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial

J Clin Endocrinol Metab. 1967 Sep;27(9):1239-48. doi: 10.1210/jcem-27-9-1239.
No abstract available

Publication types

  • Clinical Trial

MeSH terms

  • Adrenal Cortex Hormones / biosynthesis*
  • Adrenal Glands / drug effects*
  • Adrenal Glands / enzymology
  • Adrenal Glands / pathology
  • Adrenocorticotropic Hormone
  • Adult
  • Aminoglutethimide / pharmacology
  • Aminoglutethimide / therapeutic use
  • Animals
  • Anticonvulsants / pharmacology*
  • Anticonvulsants / therapeutic use
  • Breast Neoplasms
  • Child
  • Cholesterol / metabolism
  • Clinical Trials as Topic
  • Cushing Syndrome / drug therapy
  • Enzyme Therapy
  • Enzymes / pharmacology
  • Epilepsy, Absence / drug therapy
  • Female
  • Humans
  • Lyases / metabolism
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Pregnenolone / biosynthesis
  • Rats

Substances

  • Adrenal Cortex Hormones
  • Anticonvulsants
  • Enzymes
  • Aminoglutethimide
  • Pregnenolone
  • Adrenocorticotropic Hormone
  • Cholesterol
  • Lyases