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. 1971 Jul 23;173(3994):336-8.
doi: 10.1126/science.173.3994.336.

[3H]adenosine Triphosphate: Release During Stimulation of Enteric Nerves

[3H]adenosine Triphosphate: Release During Stimulation of Enteric Nerves

C Su et al. Science. .

Abstract

The isolated taenia coli of the guinea pig takes up tritiated adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate, in preference to tritiated inosine and adenine. After uptake, [(3)H]adenosine is converted and retained primarily as [(3)H]adenosine triphosphate. Tritium is released from taenia coli treated with [(3)H]adenosine upon activation of the nonadrenergic inhibitory nerves. These results are consistent with the previous evidence that adenosine triphosphate may be the transmitter from the nerves.

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