Infections due to group C streptococci in man

Am J Med. 1979 Mar;66(3):450-6. doi: 10.1016/0002-9343(79)91067-2.


Although a common cause of infection in animals, group C streptococci are rarely noted to be pathogenic in man. A total of 150,000 blood cultures obtained at the Mayo Clinic from 1968 to 1977 revealed group C streptococci in only eight patients. Acute bacterial endocarditis, meningitis, pheumonia, cellulitis and bacteremia due to group C streptococci are described in a host who had undergone immunosuppression (immunosuppressed host), and the relatively few cases previously reported are reviewed. Although severe, these infections may respond favorably to penicillin therapy. Endocarditis caused by group D streptococci is acute and destructive, and associated with early cardiac decompensation. The manifestations of cellulitis and pneumonia are similar to those when group A streptococci are causative organisms. Meningitis due to group C streptococci is acute and severe, and responds slowly to antimicrobial therapy. Colonization also occurs.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Cellulitis / diagnosis
  • Cellulitis / drug therapy
  • Cellulitis / etiology*
  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / etiology*
  • Female
  • Humans
  • Male
  • Meningitis / diagnosis
  • Meningitis / drug therapy
  • Meningitis / etiology*
  • Middle Aged
  • Pneumonia / diagnosis
  • Pneumonia / drug therapy
  • Pneumonia / etiology*
  • Sepsis / diagnosis
  • Sepsis / drug therapy
  • Sepsis / etiology*
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / microbiology*
  • Streptococcus / isolation & purification


  • Anti-Bacterial Agents