Excretion of alpha-foetoprotein in the urine of pregnant rats and hepatoma-bearing animals

Br J Cancer. 1973 May;27(5):362-9. doi: 10.1038/bjc.1973.44.

Abstract

Urine of normal rats, pregnant animals and animals bearing chemically induced hepatoma was tested with antisera to foetoproteins by the double immunodiffusion technique. Antigens were not detected in the urine of normal rats. Alpha-foetoprotein was demonstrated in the urine of pregnant rats and hepatomabearing animals.

MeSH terms

  • Amniotic Fluid
  • Animals
  • Antigens, Neoplasm / urine*
  • Blood Proteins
  • Carcinoma, Hepatocellular / urine*
  • Female
  • Fetal Proteins / urine*
  • Immune Sera
  • Immunodiffusion
  • Liver
  • Liver Neoplasms / urine*
  • Male
  • Neoplasm Metastasis
  • Organ Size
  • Pregnancy
  • Pregnancy, Animal*
  • Rabbits
  • Rats

Substances

  • Antigens, Neoplasm
  • Blood Proteins
  • Fetal Proteins
  • Immune Sera