Biochemical and morphological investigations of 30 human insulinomas. Correlation between the tumour content of insulin and proinsulin-like components and the histological and ultrastructural appearance

Diabetologia. 1973 Jun;9(3):217-31. doi: 10.1007/BF01219786.
No abstract available

MeSH terms

  • Adenoma, Islet Cell / metabolism*
  • Adenoma, Islet Cell / pathology
  • Adult
  • Aged
  • Chromatography, Gel
  • Cytoplasmic Granules
  • Diazoxide / pharmacology
  • Female
  • Histocytochemistry
  • Humans
  • Immunoassay
  • Insulin / analysis*
  • Insulin / blood
  • Insulin / metabolism
  • Insulin Secretion
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Pancreas / analysis
  • Pancreatic Neoplasms / metabolism*
  • Proinsulin / analysis
  • Proinsulin / blood

Substances

  • Insulin
  • Proinsulin
  • Diazoxide