Influence of binding on the pharmacologic activity of antibiotics

Ann N Y Acad Sci. 1973 Nov 26;226:214-24. doi: 10.1111/j.1749-6632.1973.tb20483.x.
No abstract available

Publication types

  • Review

MeSH terms

  • Adult
  • Aminoglycosides / metabolism
  • Anti-Bacterial Agents / blood
  • Anti-Bacterial Agents / metabolism*
  • Anti-Bacterial Agents / pharmacology
  • Blood Proteins / metabolism
  • Carbon Radioisotopes
  • Cell Membrane / metabolism
  • Glomerular Filtration Rate
  • Humans
  • Kidney / metabolism
  • Kinetics
  • Liver / metabolism
  • Male
  • Penicillins / blood
  • Polymyxins / metabolism
  • Protein Binding*
  • Proteins / metabolism
  • Serum Albumin / metabolism
  • Sulfonamides / metabolism
  • Tetracycline / blood
  • Time Factors
  • Uremia / blood

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Blood Proteins
  • Carbon Radioisotopes
  • Penicillins
  • Polymyxins
  • Proteins
  • Serum Albumin
  • Sulfonamides
  • Tetracycline