Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1974 May;77(1):71-94.

The Genetics of Caenorhabditis Elegans

Free PMC article

The Genetics of Caenorhabditis Elegans

S Brenner. Genetics. .
Free PMC article


Methods are described for the isolation, complementation and mapping of mutants of Caenorhabditis elegans, a small free-living nematode worm. About 300 EMS-induced mutants affecting behavior and morphology have been characterized and about one hundred genes have been defined. Mutations in 77 of these alter the movement of the animal. Estimates of the induced mutation frequency of both the visible mutants and X chromosome lethals suggests that, just as in Drosophila, the genetic units in C. elegans are large.

Similar articles

See all similar articles

Cited by 5,395 articles

See all "Cited by" articles


    1. Nature. 1966 Mar 12;209(5028):1084-6 - PubMed
    1. Mol Gen Genet. 1971;112(2):133-51 - PubMed
    1. Genetics. 1974 May;77(1):95-104 - PubMed

LinkOut - more resources