Expression of the familial hypercholesterolemia gene in heterozygotes: model for a dominant disorder in man

MeSH terms

• Alcohol Oxidoreductases / metabolism
• Cells, Cultured
• Cholesterol / biosynthesis
• Depression, Chemical
• Fibroblasts / metabolism
• Genes, Dominant*
• Heterozygote*
• Homozygote
• Humans
• Hypercholesterolemia / blood
• Hypercholesterolemia / genetics*
• Hypercholesterolemia / pathology
• Kinetics
• Lipoproteins, LDL / blood
• Lipoproteins, LDL / metabolism
• Lipoproteins, LDL / pharmacology
• Models, Biological
• Pedigree
• Protein Binding
• Receptors, Drug