Specific inhibition of a primer-dependent nucleotide chain elongation reaction by the rifamycin derivative AF/013

Arch Biochem Biophys. 1974 Oct;164(2):771-3. doi: 10.1016/0003-9861(74)90093-9.
No abstract available

MeSH terms

  • Adenine Nucleotides
  • Animals
  • Carcinoma, Hepatocellular / enzymology
  • DNA-Directed RNA Polymerases / antagonists & inhibitors*
  • Kinetics
  • Liver Neoplasms
  • Mitochondria / drug effects
  • Mitochondria / enzymology
  • Mitochondria, Liver / drug effects
  • Mitochondria, Liver / enzymology
  • Neoplasms, Experimental / enzymology
  • Polynucleotides / biosynthesis
  • Rats
  • Rifamycins / pharmacology*
  • Templates, Genetic
  • Transcription, Genetic / drug effects*

Substances

  • Adenine Nucleotides
  • Polynucleotides
  • Rifamycins
  • DNA-Directed RNA Polymerases