Abstract
The respiratory effects of dezocine and pentazocine were studied in five volunteers. Based on their effects over a 3-hour period, it was found that dezocine was 8.6 times as potent as pentazocine in terms of their respiratory depressant effects. The clinical significance of these findings remains to be determined.
MeSH terms
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Analgesics / pharmacology*
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Bridged-Ring Compounds / pharmacology*
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Carbon Dioxide / metabolism
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Cycloparaffins / pharmacology*
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Depression, Chemical
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Humans
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Male
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Narcotic Antagonists / pharmacology*
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Pentazocine / pharmacology*
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Respiration / drug effects*
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Time Factors
Substances
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Analgesics
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Bridged-Ring Compounds
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Cycloparaffins
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Narcotic Antagonists
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Carbon Dioxide
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Pentazocine