Antibodies to pneumococcal polysaccharides: relation between binding and electrophoretic heterogeneity

Science. 1968 Nov 8;162(3854):667-8. doi: 10.1126/science.162.3854.667.

Abstract

Antibodies to type III and type VIII pneumococcal polysaccharides were examined with respect to ligand binding and electrophoretic heterogeneity. Both antibodies showed apparent binding homogeneity, although multiple light chain and heavy chain electrophoretic species were demonstrated.

MeSH terms

  • Animals
  • Antibodies* / analysis
  • Antigen-Antibody Reactions*
  • Binding Sites*
  • Electrophoresis, Disc
  • Polysaccharides, Bacterial*
  • Rabbits
  • Streptococcus pneumoniae / immunology*

Substances

  • Antibodies
  • Polysaccharides, Bacterial