Inhibition of folate biosynthesis and function as a basis for chemotherapy

Adv Enzymol Relat Areas Mol Biol. 1965:27:417-68. doi: 10.1002/9780470122723.ch9.
No abstract available

Publication types

  • Review

MeSH terms

  • Aminobenzoates / biosynthesis
  • Animals
  • Binding Sites
  • Biological Transport
  • Drug Resistance, Microbial
  • Drug Synergism
  • Escherichia coli / metabolism
  • Folic Acid / biosynthesis*
  • Folic Acid Antagonists
  • Glutamates / metabolism
  • Guinea Pigs
  • Humans
  • Lactobacillus / metabolism
  • Leucovorin
  • Methotrexate / pharmacology
  • NAD
  • NADP
  • Pteridines / biosynthesis
  • Pyrimidines / pharmacology
  • Rabbits
  • Rats
  • Sulfonamides / pharmacology*

Substances

  • Aminobenzoates
  • Folic Acid Antagonists
  • Glutamates
  • Pteridines
  • Pyrimidines
  • Sulfonamides
  • NAD
  • NADP
  • Folic Acid
  • Leucovorin
  • Methotrexate