Factors affecting drug metabolism

Ann N Y Acad Sci. 1971 Jul 6;179:43-66. doi: 10.1111/j.1749-6632.1971.tb46890.x.
No abstract available

Publication types

  • Review

MeSH terms

  • Adrenalectomy
  • Age Factors
  • Animals
  • Carbon Monoxide / pharmacology
  • Carbon Tetrachloride / pharmacology
  • Circadian Rhythm
  • Cytochromes / metabolism
  • Dealkylation
  • Deamination
  • Enzyme Induction
  • Female
  • Half-Life
  • Humans
  • Hydrocortisone / pharmacology
  • Kinetics
  • Liver Circulation
  • Male
  • Mathematics
  • Metabolism / drug effects
  • Mice
  • Microsomes, Liver / enzymology
  • Microsomes, Liver / metabolism
  • Mitochondria, Muscle / metabolism
  • Mixed Function Oxygenases
  • Models, Biological
  • Morphinans / metabolism
  • Morphinans / pharmacology
  • Myocardium / metabolism
  • NAD / metabolism
  • NADP / metabolism
  • NADP / pharmacology
  • Oxidation-Reduction
  • Oxidoreductases / antagonists & inhibitors
  • Oxidoreductases / biosynthesis
  • Oxygen / pharmacology
  • Pharmaceutical Preparations / metabolism*
  • Protein Binding
  • Rats

Substances

  • Cytochromes
  • Morphinans
  • Pharmaceutical Preparations
  • NAD
  • NADP
  • Carbon Monoxide
  • Carbon Tetrachloride
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Oxygen
  • Hydrocortisone