A possible relation between pKa 1 and lipid solubility and the amounts excreted in urine of some tobacco alkaloids given to man

J Pharm Pharmacol. 1972 Feb;24(2):115-20. doi: 10.1111/j.2042-7158.1972.tb08943.x.
No abstract available

MeSH terms

  • Absorption
  • Alkaloids / metabolism
  • Alkaloids / urine*
  • Cheek / metabolism
  • Chromatography, Gas
  • Humans
  • Hydrogen-Ion Concentration
  • Lipids*
  • Mouth Mucosa / metabolism
  • Nicotine / urine*
  • Plants, Toxic*
  • Solubility*
  • Tobacco*

Substances

  • Alkaloids
  • Lipids
  • Nicotine