Allopurinol and cytotoxic drugs. Interaction in relation to bone marrow depression. Boston Collaborative Drug Surveillance Program

JAMA. 1974 Mar 4;227(9):1036-40.
No abstract available

MeSH terms

  • Adult
  • Allopurinol / adverse effects
  • Allopurinol / pharmacology*
  • Anemia, Aplastic / chemically induced*
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / pharmacology*
  • Bone Marrow / drug effects*
  • Cyclophosphamide / pharmacology
  • Depression, Chemical
  • Drug Synergism
  • Female
  • Hematopoiesis / drug effects
  • Humans
  • Leukopenia / chemically induced*
  • Male
  • Thrombocytopenia / chemically induced*
  • Time Factors

Substances

  • Antineoplastic Agents
  • Allopurinol
  • Cyclophosphamide