Ganglioneuroblastoma and fetal hydantoin-alcohol syndromes

Pediatrics. 1979 Apr;63(4):524-7.


A ganglioneuroblastoma developed in a 35-month-old boy with both the fetal hydantoin and fetal alcohol syndromes. Our case, plus two recent reports in the literature, would very likely establish the relationship between fetal hydantoin syndrome and the development of neural crest tumors. Infants exposed in utero to hydantoins should be closely observed for the development of these tumors.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Drug-Induced / etiology
  • Child, Preschool
  • Female
  • Fetal Alcohol Spectrum Disorders / complications*
  • Humans
  • Kidney Neoplasms / complications*
  • Male
  • Phenytoin / adverse effects*
  • Pregnancy


  • Phenytoin