The measurement of metabolic gas exchange and minute volume by mass spectrometry alone

Respir Physiol. 1979 Feb;36(2):261-7. doi: 10.1016/0034-5687(79)90029-x.


Metabolic gas exchange and respired minute volume were measured on 37 occasions in 9 normal adults on exercise and at rest, using the concentration of an injected gas, argon, as a measure of flow. These measurements were compared with simultaneous Douglas bag collections in which volumes were determined with a dry gas meter. The two types of measurements agreed within +/- 5%. It was concluded that this technique, designed for the remote monitoring of unconscious patients was suitable for a wide variety of clinical and experimental situations.

MeSH terms

  • Argon
  • Humans
  • Mass Spectrometry / methods*
  • Oxygen
  • Physical Exertion*
  • Respiration*


  • Argon
  • Oxygen