Effect of spironolactone on excretion of 3H-digoxin and its metabolites in rats

Eur J Pharmacol. 1974 Nov;29(1):43-51. doi: 10.1016/0014-2999(74)90168-x.
No abstract available

MeSH terms

  • Animals
  • Chloroform
  • Chromatography, Paper
  • Chromatography, Thin Layer
  • Digitoxigenin / metabolism
  • Digoxin / analogs & derivatives
  • Digoxin / blood
  • Digoxin / metabolism*
  • Digoxin / urine
  • Enzyme Induction
  • Feces / analysis
  • Female
  • Microsomes, Liver / enzymology*
  • Rats
  • Spironolactone / pharmacology*
  • Time Factors
  • Tritium

Substances

  • Tritium
  • Digitoxigenin
  • Spironolactone
  • Digoxin
  • Chloroform