Luetic hydrops--diagnosis and therapy

Laryngoscope. 1979 Jul;89(7 Pt 1):1135-44.

Abstract

Nine patients presenting at the Shea Clinic over the past eight years with a history of fluctuant hearing loss were subsequently found to have neurosyphilis. Treatment has consisted of penicillin, given by various routes, oral steroids and vasodilator therapy. We have, based on recent investigations, begun using high dose intravenous penicillin in this regimen. Results have been encouraging in two patients, with rapid improvement in hearing. A protocol outline for diagnosis and therapy of syphilis is included in the discussion.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Aged
  • Edema / etiology*
  • Female
  • Hearing Disorders / drug therapy
  • Hearing Disorders / etiology*
  • Humans
  • Male
  • Middle Aged
  • Neurosyphilis / complications*
  • Neurosyphilis / diagnosis
  • Neurosyphilis / drug therapy
  • Penicillins / administration & dosage
  • Penicillins / therapeutic use
  • Prednisone / administration & dosage
  • Prednisone / therapeutic use
  • Vasodilator Agents / therapeutic use

Substances

  • Penicillins
  • Vasodilator Agents
  • Prednisone