Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation

Nature. 1979 Mar 29;278(5703):456-9. doi: 10.1038/278456a0.
No abstract available

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / pharmacology*
  • Dexamethasone / pharmacology
  • Enzyme Inhibitors / biosynthesis
  • Guinea Pigs
  • Hydrocortisone / pharmacology
  • Lung / drug effects
  • Lung / enzymology
  • Lung / metabolism*
  • Phospholipases / antagonists & inhibitors*
  • Protein Biosynthesis
  • Thromboxane A2 / biosynthesis*
  • Thromboxanes / biosynthesis*
  • Triamcinolone / pharmacology

Substances

  • Anti-Inflammatory Agents
  • Enzyme Inhibitors
  • Thromboxanes
  • Triamcinolone
  • Thromboxane A2
  • Dexamethasone
  • Phospholipases
  • Hydrocortisone