Hodgkin's disease and leukemia

Can Med Assoc J. 1972 Mar 4;106(5):558-61.

Abstract

Four cases of acute leukemia occurring in patients with Hodgkin's disease are described. The literature on the association of these two diseases is reviewed. Acute myeloid or undifferentiated leukemias appear to be, at least in part, a complication affecting long-term survivors of Hodgkin's disease. Reed Sternberg cell leukemia is an unusual form of Hodgkin's disease and may be associated with a poor prognosis. The cytology and cytochemistry of Reed Sternberg cells are briefly discussed.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Biopsy
  • Blood Cells
  • Bone Marrow / pathology
  • Child
  • Child, Preschool
  • Female
  • Histocytochemistry
  • Hodgkin Disease / complications*
  • Hodgkin Disease / pathology
  • Humans
  • Infant
  • Infant, Newborn
  • Leukemia, Myeloid, Acute / etiology*
  • Leukemia, Myeloid, Acute / pathology
  • Lymph Nodes / pathology
  • Male
  • Middle Aged