The contribution of embryo extract to myogenesis of avian striated muscle in vitro

Proc Natl Acad Sci U S A. 1972 May;69(5):1131-5. doi: 10.1073/pnas.69.5.1131.

Abstract

Myogenesis of avian striated muscle in vitro requires the presence of serum and embryo extract. The serum requirement can be satisfied by insulin. Embryo extract contributes at least two factors, one of which promotes the fusion of myoblasts, whereas the other promotes the development of myotubes.

MeSH terms

  • Animals
  • Cell Differentiation / drug effects*
  • Cells, Cultured
  • Centrifugation
  • Chick Embryo
  • Chickens
  • Culture Media
  • Insulin / pharmacology
  • Microscopy, Electron
  • Muscle Development
  • Muscles / cytology
  • Muscles / drug effects
  • Muscles / embryology*
  • Tissue Extracts / pharmacology*

Substances

  • Culture Media
  • Insulin
  • Tissue Extracts