Ferritinaemia in leukaemia and Hodgkin's disease

Br J Cancer. 1973 Mar;27(3):212-7. doi: 10.1038/bjc.1973.26.

Abstract

The serum ferritin concentration is increased in both acute myeloblastic leukaemia and Hodgkin's disease. In acute leukaemia the mean concentration is about ten times the normal level and is associated with a high concentration of transferrin-bound iron. In Hodgkin's disease abnormal ferritinaemia is associated with a low concentration of transferrin-bound iron and appears to result from a block of reticuloendothelial iron release. Increased concentrations of circulating ferritin have also been observed in a few cases of chronic leukaemia and myelomatosis.

MeSH terms

  • Acute Disease
  • Anemia / blood
  • Chronic Disease
  • Female
  • Ferritins / blood*
  • Hodgkin Disease / blood*
  • Humans
  • Leukemia / blood*
  • Leukemia, Myeloid, Acute / blood
  • Leukocyte Count
  • Male
  • Multiple Myeloma / blood

Substances

  • Ferritins