Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species
- PMID: 4526202
- PMCID: PMC388412
- DOI: 10.1073/pnas.71.6.2169
Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species
Abstract
The ability of fibroblasts to perform unscheduled DNA synthesis (a measure of excision-repair) after UV irradiation was measured radioautographically for seven species at several times after several UV fluences. Both the initial rate and the maximum incorporation of [(3)H]dThd increased with the life-span of the species (shrew, mouse, rat, hamster, cow, elephant, man). Unscheduled DNA synthesis was approximately proportional to the logarithm of life-span.
Similar articles
-
DNA repair and life span of mammals.Basic Life Sci. 1975;5B:801-4. doi: 10.1007/978-1-4684-2898-8_59. Basic Life Sci. 1975. PMID: 1191200
-
The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals.Mech Ageing Dev. 1981 Jun;16(2):181-9. doi: 10.1016/0047-6374(81)90094-4. Mech Ageing Dev. 1981. PMID: 7266079
-
Excision repair (dimer excision, strand breakage and repair replication) in primary cultures of eukaryotic (bovine) cells.Exp Cell Res. 1972 Sep;74(1):67-80. doi: 10.1016/0014-4827(72)90482-x. Exp Cell Res. 1972. PMID: 4627418 No abstract available.
-
Unscheduled synthesis of DNA during mammalian spermatogenesis in response to UV irradiation.J Exp Zool. 1973 Mar;183(3):375-82. doi: 10.1002/jez.1401830311. J Exp Zool. 1973. PMID: 4697408 No abstract available.
-
Relationship between DNA repair capacity and cellular aging.Gerontology. 1976;22(1-2):28-55. doi: 10.1159/000212123. Gerontology. 1976. PMID: 1107150 Review.
Cited by
-
YIPF2 regulates genome integrity.Cell Biosci. 2024 Sep 5;14(1):114. doi: 10.1186/s13578-024-01300-x. Cell Biosci. 2024. PMID: 39238039 Free PMC article.
-
Enhancement of postreplication repair in Chinese hamster cells.Proc Natl Acad Sci U S A. 1976 Jul;73(7):2396-400. doi: 10.1073/pnas.73.7.2396. Proc Natl Acad Sci U S A. 1976. PMID: 1065893 Free PMC article.
-
Cellular aging--clonal senescence. A review (Part I).Am J Pathol. 1977 Nov;89(2):484-512. Am J Pathol. 1977. PMID: 335895 Free PMC article. Review. No abstract available.
-
Senescent cell turnover slows with age providing an explanation for the Gompertz law.Nat Commun. 2019 Dec 2;10(1):5495. doi: 10.1038/s41467-019-13192-4. Nat Commun. 2019. PMID: 31792199 Free PMC article.
-
The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis.Proc Natl Acad Sci U S A. 1974 Sep;71(9):3363-6. doi: 10.1073/pnas.71.9.3363. Proc Natl Acad Sci U S A. 1974. PMID: 4530308 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
